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The Missouri Rex was a curly-haired cat that appeared in the early 1990s. It was a shorthaired cat with smooth wavy fur, a semi-cobby body, large low set ears, and "loopy" non-brittle whiskers. The rex mutation was established to be a recessive gene and when it was test-bred to both Devon and Cornish Rexes, only straight-haired kittens resulted. This showed that the Missouri Rex was a different mutation to both of those. By the late 1990s, there were only three Missouri Rex in existence due to financial mismanagement of the breed which led to most of the cats being destroyed.

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